Potentialities of Digital Capillaroscopy in the Diagnostics of Oedema Syndrome

Yury I. Gurfinkel; Maria L. Sasonko

doi:10.18287/JBPE17.03.030401

Authors

Yury I. Gurfinkel Laboratory of blood microcirculation, Medical Research and Educational Center, Lomonosov Moscow State University, Russia
Maria L. Sasonko Research Clinical Centre, JSC Russian Railways, Moscow, Russia

DOI:

https://doi.org/10.18287/JBPE17.03.030401

Keywords:

digital capillaroscopy, oedema syndrome, remodelling coefficient, perivascular zone

Abstract

The paper is devoted to the study of digital capillaroscopy potentialities in the assessment of oedema syndrome by the example of a group of patients with diseases of cardiovascular system (CVS). 75 patients were examined, 47 of them with CVS diseases and 28 healthy volunteers. Alongside with the standard examination customary for this pathology, the capillaroscopy of hand finger nail bed was carried out in all patients. The study has revealed considerable dilation of transitional segments of capillaries, increase of the capillary bed remodelling coefficient and the linear dimension of perivascular zone in patients with clinically expressed oedema syndrome. In the group of patients with CVS diseases without clinically expressed oedema, we revealed the statistically significant increase of perivascular zones and remodelling coefficient of capillary bed. The digital optical capillaroscopy can be applied in the clinical practice for early diagnostics of the hidden oedema syndrome and as a quantitative method of diagnostics for clinically expressed oedema and assessment of drug therapy efficiency.

References

G. Yu. Suvorova, and A. I. Martynov, Oedema syndrome: clinical presentation, differential diagnostics, treatment, GEOTARMedia, Moscow, Russia (2009) [in Russian].

V. Yu. Mareyev, M. O. Danielyan, Yu. N. Belenkov, et al, “Epidemiologic examination of patients with CHI in real practice (by medical aid appealability),” EPOKhA-O-KhSN study, Serdechnaya nedostatochnost’ 4(3), 116-120 (2003) [in Russian].

P. Ponikowski et al., “ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure,” European Journal of Heart Failure 18, 891-975 (2016).

A. J. Houben, J. H. Beljaars, L. Hofstra, A. A. Kroon, and P. W. de Leeuw, “Microvascular Abnormalities in Chronic Heart Failure: A Cross-Sectional Analysis,” Microcirculation 10(6), 471-478 (2003).

Yu. I. Gurfinkel’, O. V. Makeyeva, and V. A. Ostrozhinskii, “Peculiarities of microcirculation, endothelial function, and the pulse wave propagation velocity in patients with initial stages of arterial hypertension,” Funktsional’naya diagnostika 2, 18-25 (2010) [in Russian].

Yu. I. Gurfinkel’, O. Yu. At’kov, M. L. Sasonko, and R. M. Sarimov, “New approach to the integral assessment of the cardiovascular system condition in patients with arterial hypertension,” Rossiyskii kardiologicheskii zhurnal 105(1), 101-106 (2014).