Effect of Upconversion Nanoparticles on Erythrocytes

Anna A. Doronkina; Alexander B. Pravdin; Artyom M. Mylnikov; Vyacheslav I. Kochubey; Irina Yu. Yanina

doi:10.18287/JBPE24.10.020309

Authors

Anna A. Doronkina Saratov State University, Russian Federation
Alexander B. Pravdin Saratov State University, Russian Federation
Artyom M. Mylnikov Saratov State Medical University, Russian Federation
Vyacheslav I. Kochubey Saratov State University, Russian Federation
Irina Yu. Yanina Saratov State University, Russian Federation

DOI:

https://doi.org/10.18287/JBPE24.10.020309

Keywords:

erythrocytes, nanoparticles, morphology, membrane viscosity

Abstract

We have shown experimentally that the interaction of upconversion nanoparticles with erythrocytes leads to changes in cell size and shape. One of the reasons for this is thought to be a change in the viscosity of erythrocyte membrane. Using a fluorescent probe, pyrene, we have shown that this nanoparticle−induced change in membrane viscosity depends on the nature of the nanoparticle shell (cover).

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