Enhanced Interaction of Ciprofloxacin with Humic Substances and Magnetite-Silica-Nanoparticles in Multicomponent System: Spectrophotometric and Electrokinetic Studies
Artur Dzeranov
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Moscow Aviation Institute (National Research University), Russia
Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia
Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia
Paper #9061 received 18 Jan 2024; revised manuscript received 26 Mar 2024; accepted for publication 27 Mar 2024; published online 26 Apr 2024
DOI: 10.18287/JBPE24.10.020301
Abstract
We evaluated the effect of dissolved organic matter (DOM) on the sorption of antibiotic ciprofloxacin (CIP) by magnetite-silica nanoparticles (NPs). For this purpose, magnetite NPs (M) modified with organosilanes (tetraethoxysilane and 3-aminopropyltriethoxysilane, TA) were used as a natural model of colloidal particles and a sorbent. Absorption spectra did not manifest any interaction between CIP and humic preparation (HP, sodium salt of humic acids) in aquatic system at pH from 6 to 8. On the contrary, the introduction of the MTA NPs into a bicomponent system of CIP incubated with HP lead to more than twice increased CIP sorption. Results of electrokinetic measurements in terms of zeta potential figured out the interaction mechanism in the CIP-HP-NPs system. In the three-component system, the MTA surface completely recharged from negative to positive, and importantly this effect is pH-dependent. The MTA zeta potential varied from −15 (pH 6) and −30 mV (pH 8) to +10 (pH 6) and +2 (pH 8). The study provides novel information on very actual topic in biomedical and ecological research since NPs are increasingly produced and implemented for various medical and environmental applications, including sorption of emerging ecotoxicants (pharmaceuticals), but the assessment of naturally occurring DOM in water should not be ignored
Keywords
References
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